All articles by Andy Extance – Page 10
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Research
Lilly pushes continuous drug production limits
Integrated flow synthesis and purification process for prexasertib meets high industry standards
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Research
Scientists get charged up over titanium dioxide
Groups debate usefulness of conventional +4 titanium oxidation state compared to +2.5 charge state
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Business
First biomarker-driven approval exemplifies cancer immunotherapy progress
Landmark decision is latest step in field’s impressive – but not wholly untroubled – advance
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Research
Stick-up experiment lets scientists 'see' hydrogen atoms
Upright structures offer hard-to-get direct AFM measurements
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Business
Merck KGaA to buy Chematica
Retrosynthesis tool will gain computational muscle and integrate with Sigma–Aldrich catalogue
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Business
Brexit raises regulatory worries
Risk of doubling legal burden for industry undermines referendum’s ‘red-tape cutting’ claims
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Feature
Covalent inhibitor drugs
Exceptions to a long-held rule against chemically bonding to biological targets are powering new cancer medicines, finds Andy Extance
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Business
How do chemical firms last hundreds of years?
What distinguishes companies that thrive from others that failed?
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Research
Catalyst fuels hydrogen car vision
Platinum–molybdenum carbide expedites hydrogen formation from water and methanol
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Careers
Forging a future for glassblowing
Creating scientific instruments is a rare but highly desirable skill
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Research
Ultrafast lasers promise to make lead ‘look like’ gold
Theoretical study suggests atomic mimicry could reshape spectroscopy, information processing – and even chemical reactivity
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Research
Do hydrogen bonds have covalent character?
Scientists wrangle over disagreement between charge transfer measurements
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Business
University–industry collaborations aspire to pharmaceutical innovation
Three new UK partnerships illustrate drug research co-operation approaches that are growing in popularity
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Research
Sulfur linkage takes click chemistry in a different direction
Thionyl tetrafluoride-based ‘sleeping beauties’ enable click chemistry in a tetrahedral shape
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Research
Biological fuel cell could power cleaner ammonia production
Harnessing nitrogenase enzyme makes key fertiliser material while generating electricity
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Feature
Chemical fossils
Andy Extance finds out what organic molecules made by microorganisms and plants far in the past can tell us about climate
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Research
‘Metallic hydrogen’ claim faces fiery scrutiny
State of hydrogen predicted to be a room temperature superconductor reportedly seen – but the methods used are being questioned
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Research
Solid 3D NMR evidence reaches the surface
200-fold signal boost means silica spectroscopy could communicate catalyst configurations
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Research
Drug binding simulations promise to get personal
Fast, reliable new molecular dynamic simulation methods set to speed up research are under investigation by GSK
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Research
Record polyhedron boosts molecular self-assembly
New supramolecular system shape found by chance inspires improved design principle