All articles by Chris Nawrat – Page 2
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Opinion(‒)-Pavidolide B
An innovative approach to making five-membered carbon rings makes for a strikingly short synthesis
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Opinion(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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Opinion(+)-Zincophorin methyl ester
New and old reactions combine for an elegant and concise synthesis
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Opinion6-epi-Ophiobolin N
When it comes to cascade reactions, radicals are king of the ring-formers
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OpinionBatzelladine B
Taming basic and reactive nitrogen atoms makes alkaloids more attractive targets, says BRSM
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Opinion(–)-Jiadifenolide
BRSM wonders what makes a route so good it becomes the last total synthesis of a complex target
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OpinionLimaspermidine and deethylibophyllidine
Desymmetrisation offers a neat way to add tricky features, says BRSM
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OpinionRubriflordilactone A
Sometimes it’s worth building aromatics instead of buying them, says BRSM
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OpinionLycopodium alkaloids
Not all natural products are created equal. BRSM looks at a flexible route to some perennial favourites
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OpinionPsylloborine A
Late stage dimerisation is a tantalisingly elegant but risky strategy for total synthesis, says BRSM
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OpinionMandelalide A
New reactions need to belong in a synthesis, says BRSM, not be forced in for show
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OpinionIndoxamycins A, C and F
BRSM gets to the core of a divergent synthesis of this natural product family
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