Biology – Page 10
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Research
Artificially expanded genetic alphabet evolves enzymes for the first time
Libraries of short DNA sequences incorporating synthetic nucleotides perform better as enzymes than ordinary DNA
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Feature
Celebrating Louis Pasteur’s bicentenary
Mike Sutton reflects on the dramatic discoveries of Louis Pasteur, born 200 years ago
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Feature
The brain chemicals that control what we enjoy
Researchers are trying to understand how orexins influence our appetites, and whether we can use them to treat addiction and obesity, explains Andy Extance
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Careers
Work or study… or work and study?
How employers are helping employees to gain new qualifications, including PhDs
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Careers
Carving out a career as an amateur scientist
Lacking a degree has not stopped Sebastian Cocioba making waves in the world of biotechnology
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Opinion
Martin Chalfie: ‘I decided I wasn’t going to be a scientist’
The Nobel prizewinner on breaking a promise to himself and the test he had to pass to receive his medal
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Research
Diverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds
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Research
NMR spectroscopy used to guide evolution of better enzymes
Identifying mutagenic ‘hotspots’ could speed development of new proteins
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Opinion
Why glycans?
Glycoscience is turning out to be more interesting than anyone might have imagined
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Feature
How click conquered chemistry
Katrina Krämer tells the story of how click and bioorthogonal chemistry came to win the 2022 Nobel prize
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Opinion
A promising breakthrough in liquid condensate compartmentalisation
Tears are RNA solvent droplets that could help engineer new functions into bacteria
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Opinion
Nobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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News
Explainer: why have bioorthogonal and click chemistry won the 2022 Nobel prize?
Carolyn Bertozzi, Morten Meldal and Barry Sharpless have won the 2022 Nobel prize in chemistry – find out why
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Business
Alzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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Business
Silky smooth tissue regeneration
Serigen mediproducts is harnessing one of India’s biggest industries to help heal wounds and rebuild flesh and bone
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Business
An evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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Opinion
Cracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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Feature
Can we clean Covid from the air around us?
Nina Notman talks to the experts about what is needed to remove pollutants and even infectious diseases from the air inside our homes, schools and offices
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News
Genetically modified purple tomatoes receive US approval
Home growers will be able to purchase seeds from spring 2023
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Opinion
Contribute to defeating malaria
The Medicines for Malaria Venture needs new compounds for screening and more chemists to join its open-souce drug discovery project