Biotechnology and bioengineering – Page 2
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ResearchAutonomous platform engineers enhanced proteins
AI-powered robotic system designs and optimises proteins following its own ‘scientific method’
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BusinessPharmaceuticals roundup 2023
Regulatory and pricing reforms have topped industry agendas in 2023, while weight loss drugs surged and Covid-19 therapies waned
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BusinessDanaher completes $5.7 billion Abcam acquisition
Deal proceeded despite significant opposition from founder and ex-chief Jonathan Milner
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ResearchBiocatalysis breakthrough enables synthesis of lactam building blocks for drugs
Enzymatic cyclisation of oxazolone reagents offers a cheap and simple route to important antibiotic precursor
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ResearchDNA-damaging device could make mutant discovery safer and simpler
Cool microplasma jets create a stream of radicals that induce mutations
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BusinessUK becomes first country in the world to authorise a Crispr-based gene therapy
Treatment aims to cure patients with β-thalassaemia and sickle-cell disease
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ResearchSynthetic yeast genome project creates strain with over 50% synthetic DNA
Entirely artificial organism opens up door to designer yeast with biotechnology applications
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ResearchControlling insulin activity in cells with ‘DNA origami’
Insulin–DNA nanorods elicit geometry-dependent insulin activity, which could lead to more targeted treatments for diabetes
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ResearchGenetic-editing of chickens protects them from catching the flu
Approach heralds new way to make animals resistant to disease
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Research’This is just the beginning’: RNA editing set to democratise viral engineering
Crispr-based system could ease development of novel RNA therapies
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ResearchChemical industry hasn’t yet developed an appetite for biocatalysis, survey finds
Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis
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ResearchSynthetic peptide mimics can act as antivirals
Peptoids disrupt enveloped viruses’ lipid membranes as well as targeting fungi and bacteria
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NewsJustice for Henrietta Lacks as family reaches settlement with Thermo Fisher
Company was accused of profiting from HeLa cells derived from Lacks’ tumour without her family’s approval
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ResearchClick chemistry offers new, efficient process to produce unique cancer-fighting antibodies
Chemical approach is fast and flexible and could be an alternative o using protein engineering
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BusinessAntibodies face Alzheimer’s reality
Companies are convincing regulators, but will doctors use them, and will providers pay for them?
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BusinessBiogen to cut 1000 more jobs by 2025
Biotech giant has also agreed to buy Reata Pharmaceuticals for $7.3 billion
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ResearchProtein folding stability set to be unravelled on a massive scale
Technique can analyse a million protein sequences at a time to provide data for machine learning models
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ResearchCrispr editing reduces poplar lignin content
Gene-edited wood could reduce waste and save energy during pulping process
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ResearchAir monitor detects airborne virus particles in real time
Device that detects Sars-CoV-2 could be adapted to monitor other respiratory pathogens
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NewsEuropean Commission set to propose an overhaul of rules for gene-edited crops
Leaked document reveals light touch regulation planned for crops engineering using precision techniques