Organic chemistry – Page 15
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News
Chemistry Nobel laureate Ei-ichi Negishi dies at 85
Discoverer of the Negishi coupling, who did synthetic organic chemistry research at Purdue for four decades, has passed away
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Research
Genetically engineered microbes convert waste plastic into vanillin
Plastic bottle becomes industrially useful product thanks to biosynthetic transformation
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Research
Synthetic overhaul for hepatitis C drug could ease manufacturing demands
Chemists hope their five-step synthesis will increase global accessibility of uprifosbuvir and other lifesaving antivirals
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Research
Iodine revealed to be killer species that destroys tin-based perovskites
New insights into the mechanism that inactivates tin solar cells could lead to greener, more efficient devices
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Research
Anti-electrostatic halogen bonding shown in solution for the first time
UV-vis spectroscopy and computational analysis explore nature of counterintuitive anionic interaction
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Research
Blue light triggers ‘unprecedented’ reaction in old catalyst
Traditional iridium intermediate switches from allylic substitution to cross coupling when exposed to blue light
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Opinion
Free radicals for post-translational modification
A technique for forming new carbon–carbon bonds at specific sites in proteins
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Research
Reaction confined between copper nanopyramids transforms carbon dioxide into ethylene glycol
Copper arrangement promotes C–C coupling and lowers formation barrier for a key intermediate
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Feature
Computer-guided retrosynthesis
Machine learning-based systems hope to outperform expert-guided reaction planning technology, finds Andy Extance
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Research
Uncovering new transformations by using electricity as a reagent
Song Lin explains the power of electrochemistry and how he fosters an inclusive environment for his research group
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Research
Re-evaluating pyridine’s role in chlorination reaction
Well-established mechanism for chlorination using dichloroiodobenzene together with pyridine proven wrong
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Opinion
Exploring the potential of nanoarchitectonics
Combining self-assembly techniques from across scientific disciplines could allow us to precisely build any material structure
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Research
Peptide ligation strategy unlocks diverse range of structural motifs
Approach expected to influence design of protein–protein interaction inhibitors
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Research
Nitrogen deletion reaction offers ‘new way to think about molecular editing’
Reagent inspired by decades-old research could save chemists a lot of headache when it comes to modifying molecules’ skeleton
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Research
Automated organic synthesis made easier with capsule-based console
Integrated console to synthesise drug-like molecules requires minimal user input
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Research
Alkali cations boost carbon dioxide reduction into feedstock chemical
Discovery enables continuous-flow electrolysers with industrial potential
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Research
AI enantioselectivity predictor set to power computational catalyst screening
Workflow involves mapping a reaction representation onto the activation energy of the stereocontrolling step
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Research
Rapidly alternating polarity stars in selective electrochemical reduction
Rapidly fluctuating AC targets specific carbonyl groups in the presence of several reducible groups
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News
Bots bring chemistry research tools to Twitter
Cheminformatic tool can deliver retrosynthetic analysis