Cryo-electron microscopy developed by Jacques Dubochet, Joachim Frank and Richard Henderson has transformed biochemistry
Just three years after super-resolution fluorescence microscopy another microscopy technique – cryo-electron microscopy (cryo-EM) – has just been propelled into the limelight with the 2017 chemistry Nobel prize. Dubochet, Frank and Henderson developed a method that made it possible to see the molecules of life for the first time as three-dimensional structures at atomic resolution.