All RNA articles
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ResearchSelf-assembling RNA strands ‘tamed the chemical chaos’ in prebiotic mixtures
New research explores mechanisms that boost RNA’s stability and resistance to hydrolysis
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FeatureMore than a mirror-image: left-handed nucleic acids
Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports
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Research’This is just the beginning’: RNA editing set to democratise viral engineering
Crispr-based system could ease development of novel RNA therapies
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CareersWorking at the forefront of AI
Petrina Kamya’s curiosity has led her across sectors to become a leader in drug discovery
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ResearchRNA building block uracil recovered from near-Earth asteroid Ryugu
Japanese mission returns pristine sample to bolster idea that prebiotic chemicals could have been delivered by meteorites
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OpinionA promising breakthrough in liquid condensate compartmentalisation
Tears are RNA solvent droplets that could help engineer new functions into bacteria
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OpinionCracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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OpinionFrom prebiotic soup to fine-grained RNA world
Theories about how life emerged need to be closely attuned to conditions on the early Earth
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ResearchFreeze–thaw cycles could explain how ancient RNA replicated without enzymes
Discovery solves puzzle of RNA world hypothesis
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ResearchAll of life’s nucleic acids could have extraterrestrial origins
All five nucleobases of RNA and DNA found in three meteorites
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NewsChemistry Nobel laureate Sidney Altman dies at 82
Canadian–American molecular biologist won the 1989 prize for discovering RNA’s catalytic ability
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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BusinessNew antiviral impresses against Covid-19
Merck & Co and Ridgeback’s molnupiravir reduces risk of hospitalisation and death, and may work against other coronaviruses
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NewsChemistry Nobel predictions range from free-radical chemistry to MOFs
Data-crunching goes up against gut feeling as the chemistry community weighs in on their favourites for the world’s top chemistry prize
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ResearchMachine learning accurately predicts RNA structures using tiny dataset
Development could lead to better understanding of RNA and new medicines
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ResearchNew class of biomolecule baffles scientists
GlycoRNAs found across several cell types and organisms
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FeatureDrugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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BusinessEarly indications suggest Pfizer–BioNTech’s Covid-19 vaccine is effective
Company claims 90% efficacy at preventing disease, but experts call for data rather than press releases
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ResearchEntirely new way of sensing iron discovered in bacteria
Novel class of riboswitches can directly and selectively sense iron
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FeatureUnnatural selection in chemical systems
Great strides have been made in the lab with chemical systems that ape life’s behaviour