Supramolecular cage unlocks mild aldehyde reduction strategy

An image showing the Fe4L6 cage

Source: © Mark Symes/University of Glasgow

Computational analysis reveals how encapsulation stabilises protonated oxocarbenium ion of furfural, which makes the carbonyl moiety easier to reduce

Reducing aldehydes can be challenging under mild, acid-free conditions, but researchers at in the UK have shown how supramolecular cages can catalyse the reaction and substantially boost the yield.