Autonomous platform engineers enhanced proteins

By Fernando Gomollón-Bel2024-01-25T09:30:00

Source: CC-BY 4.0 - Rapp, J.T., Bremer, B.J. & Romero, P.A. https://doi.org/10.1038/s44286-023-00002-4

AI-powered robotic system designs and optimises proteins following its own ‘scientific method’

A new robotic platform produces proteins with improved properties in a fully autonomous manner. Moreover, the system is able to experimentally assess these proteins and, thanks to artificial intelligence, interpret the results and then redesign the proteins’ amino acid sequences to boost their functionalities further. In a preliminary test to bolster the thermal tolerance of glycoside hydrolases, the robot increased the proteins’ temperature resistance by at least 12°C.