PFAS linked to foetal metabolism disorders

Foetus

Source: © Neil Bromhall/Science Photo Library

‘Forever chemicals’ in the livers of unborn children can alter lipid metabolism and may increase the risk of metabolic disease in adulthood

An analysis of foetal liver tissue offers new insight into the metabolic effects of polyfluoroalkyl substances (PFAS). The findings show that exposure to these ‘forever chemicals’ alters lipid metabolism in unborn children, and could increase the risk of metabolic disease later in life.

While PFAS are associated with negative health impacts, the metabolic pathways linking PFAS exposure to human disease are unclear, and most studies into these effects have focused on exposure in adults. Scientists from the UK and Sweden have now investigated the metabolic effects of PFAS in the foetal liver tissue.