Gene assays reveal disruption to cell receptors crucial for hormonal and metabolic control
Everyday plastic food packaging contains chemicals that can disrupt the working of human cells, two new studies from a Norwegian group reveal. The effects include interfering with cell receptors that are crucial for hormonal and metabolic control, as well as our body clock.
The Norwegian lab tested chemicals from plastic items purchased in five countries – US, Germany, the UK, South Korea and Norway – against four cell receptors.1 Non-target high-resolution mass spectrometry and reporter gene assays revealed that 18 out of 36 plastics contain chemicals that activate estrogen receptors and 14 contain compounds that block androgen receptors. ‘There are thousands of unique chemicals present in plastics and they are disrupting endocrine and metabolic receptors,’ says Molly McPartland, a PhD candidate in the lab of Martin Wagner at the Norwegian University of Science and Technology.