AI predicts vape flavours can break down into potentially harmful compounds when heated

An artificial intelligence-based approach has predicted hundreds of harmful compounds that could form when e-cigarette flavour chemicals are heated in vaping devices. The research adds to mounting evidence concerning the safety of vaping, finding that many of the predicted pyrolysis products from flavours are classed as either acutely toxic, health hazards or irritants. What’s more, their impact on health might take years to emerge, say the researchers.

E-cigarettes work by heating up an e-liquid, or e-juice, to produce an aerosol that comprises nicotine, solvents – including propylene glycol and glycerol – and flavourings, which a user then inhales. There are tens of thousands of different flavour e-liquids on the market and ingredients are picked from at least 180 commercially available flavour compounds, which were originally developed for the food industry and deemed safe for consumption. However, the long-term health risks of heating and inhaling these chemicals remain unknown.