Medicinal chemistry
The latest chemistry news and research on medicinal chemistry including drug discovery, clinical trials, toxicology and science of disease, from the Royal Society of Chemistry's magazine, Chemistry World
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Research
A new gold standard in selective nitrobenzene hydrogenation
Reaction proceeds through a previously unidentified mechanism
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News
microRNA discovery wins Nobel prize in medicine
Research on tiny RNA molecules unlocked mysteries of gene regulation and cell differentiation
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Business
US approves schizophrenia drug with new mode of action
Cobenfy promises to better address negative symptoms than existing antipsychotics
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Webinar
Emerging routes to new therapeutics: Highlights from winning Horizon Prize teams
Join us on 13 November to discover how new therapeutics have the potential to address unmet medical needs
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Webinar
The science and promise of liquid biopsies
Join us on 4 December to learn more about the science of liquid biopsies from leaders in the field
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Opinion
A chemist in the flower garden
The beautifully complex molecules plants produce are as inspiring as the blooms themselves
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Feature
Blood biopsies for cancer
Testing small amounts of blood for the presence of disease markers could revolutionise how we detect cancer. Clare Sansom reports
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Research
Yellow food dye could give doctors a new way to look beneath the skin
Tartrazine can safely and reversibly turn the skin of mice transparent
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Business
Tea tree oil faces ban in UK and EU over reprotoxicity
Defenders question relevance of animal safety data that triggered decision
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Business
US industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns
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Opinion
Being wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
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Opinion
GLP-1 drugs could be more than a win–win for weight loss
Semaglutide and tirzepatide are changing lives, and could change our attitudes
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Feature
The GLP-1 weight loss revolution
Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next
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Opinion
Proteins’ shape and function are two sides of the same coin
A new perspective on the relationship between chemistry and biology
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Business
MDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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Research
Potential new class of antibiotics takes on flesh-eating infections
Peptide-mimicking compounds target bacterial cell walls
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Research
Innovative antibacterial strategy shows promise for treating infections
New antibiotic mechanism sees molecule infiltrate bacterial cells and destroy them from the inside
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Research
Analytical chemistry tools point to the future of personalised medical diagnostics
Molecular fingerprinting techniques outperform standard blood tests for detecting the onset of many diseases
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Opinion
Medicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge