Medicinal chemistry – Page 9
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NewsAlarm sounded after chemists discover new analogue of ketamine in Australia
Long-term health effects of novel psychoactive substance are unknown
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ResearchGut bacterium found to destroy nicotine offers liver health benefits for smokers
Discovery might lead to therapy for non-alcoholic fatty liver disease
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ArticleInspiring a new era of patient-centric medicines
Christian Jones discusses new formulations for drug delivery that put people first
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ResearchDiverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds
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ResearchAmide library created at speed with machine learning and stopped-flow chemistry
Approach used 90% less starting material than continuous flow equivalent
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FeatureTiny delivery systems for cancer drugs
Encapsulating anticancer agents in nanoparticles can make them gentler on the rest of the body. Clare Sansom reports
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OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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BusinessAlzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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BusinessAn evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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OpinionThe end of a long race?
The finishing line of the Covid-19 pandemic may be in sight, but we mustn’t stop running just yet
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FeatureCan we clean Covid from the air around us?
Nina Notman talks to the experts about what is needed to remove pollutants and even infectious diseases from the air inside our homes, schools and offices
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OpinionContribute to defeating malaria
The Medicines for Malaria Venture needs new compounds for screening and more chemists to join its open-souce drug discovery project
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Feature50 years of artemisinin
Jamie Durrani tells the story of how a wonder drug against malaria was discovered from a plant in a secret Chinese military project
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NewsFrench inquiry censures lab that promoted hydroxychloroquine to treat Covid
Report raises awkward questions about prominent study on antimalarial conducted in Didier Raoult’s lab
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ResearchYeast engineered to ferment sugars into chemotherapy drug precursors
Semisynthesis offers new route to anticancer drug vinblastine
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BusinessArrayit chief convicted of fraud over blood testing
Mark Schena misrepresented the company’s value to investors and defrauded public and private insurers
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OpinionConfusing cannabinoids
Decomposition during GC–MS analysis can thwart efforts to determine if a product is legal
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WebinarHow to profit from recent innovations in small molecule drug discovery
Reduce risk, cost and wasted time in the new era of small molecule drug discovery