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Chris Nawrat

Chris Nawrat obtained his PhD in total synthesis in the UK, completing several brightly coloured natural products. After a postdoctoral stint at an Ivy League school, he remained in the US, where he now works as a process chemist at a major pharmaceutical company.

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Opinion
(–)-Bipolarolide D
2024-06-12T08:30:00
A rare example of a [6 + 2]-cycloaddition
Opinion
(+)-Heilonine
2024-02-28T09:34:00
A short route that brings together the classical and cutting-edge
Opinion
(+)-iso-Phomopsene (and friends)
2023-09-26T13:30:00
A non-obvious combination unleashes the power of electrocyclisation
Opinion
(+)-KB343
2023-06-28T08:31:00
A total synthesis that uses a cunning trick to negotiate nitrogen
Opinion
(–)-Quinine
2023-02-01T09:44:00
Stop counting steps and move on to some one-pot reactions
Opinion
(–)-Tetrodotoxin
2022-10-12T08:40:00
Choosing an efficient route to a classic target
Opinion
Bastimolide B
2022-06-23T13:32:00
Fewer steps with boron chemistry
Opinion
(+)-Quassin
2022-02-25T14:19:00
A rare modern-day sighting of a quinone intermediate
Opinion
(+)-Njaoamine I
2021-11-04T14:30:00
Ringing in the advantages of alkyne methathesis
Opinion
(–)-Norzoanthamine
2021-06-30T08:34:00
A synthesis combining radical methods old and new
Opinion
Euonyminol
2021-02-18T14:31:00
Overcoming the challenges of working with highly polar molecules
Opinion
(+)-Vancomycin aglycon
2020-10-22T13:23:00
Optimising for efficiency deserves credit too
Opinion
(–)-Taxol
2020-06-25T13:41:00
Following nature’s lead
Opinion
(–)-Curvulamine
2020-02-25T14:56:00
Working through the Pains of pyrrole
Opinion
(±)-Rhabdastrellic acid A
2019-10-31T14:29:00
A triterpene that looks innocuous until it reveals the highly strained conformation of its rings
Opinion
(+)-Microladallene B
2019-06-21T09:27:00
A weird structure is enough to spark chemists’ interest, even without any obvious use
Opinion
Jorunnamycin A
2019-03-05T14:27:00
Sometimes synthetic ingenuity can trump nature
Opinion
(−)-Gelsemoxonine
2018-10-23T14:27:00
Harnessing the power of the nitro group
Opinion
Hosieine A
2018-06-27T12:12:00
In defence of name calling
Opinion
(–)-Callyspongiolide
2018-02-14T11:00:00
Ringing the changes with some unconventional chemistry

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