Biology – Page 4
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FeatureMore than a mirror-image: left-handed nucleic acids
Now a biological reality, researchers are starting to figure out the many roles of left-handed nucleic acids such as Z-DNA – from immunity to controlling our genetics. Rachel Brazil reports
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ResearchHeavy metals are potential ovarian toxicants
Exposure to metals like arsenic, cadmium and mercury linked to reduced egg production, earlier menopause for middle-aged women
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ResearchUnravelling enzyme pathway of Taxol precursor brings synthetic production of cancer medicine closer
Expression of nine genes in tobacco plants led to formation of complex precursor of drug
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ResearchE. coli rewired to shift carbon flow towards C4 chemicals
Bioengineering strategy creates evolutionary advantage linking cell growth with product formation
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ResearchPFAS linked to foetal metabolism disorders
‘Forever chemicals’ in the livers of unborn children can alter lipid metabolism and may increase the risk of metabolic disease in adulthood
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ResearchD-trypsin synthesis enables sequencing of mirror-image proteins
Reversing the chirality of a protein-digesting enzyme could aid the development of mirror-image therapeutics
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ResearchAutonomous platform engineers enhanced proteins
AI-powered robotic system designs and optimises proteins following its own ‘scientific method’
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FeatureTesting times for tuberculosis
Nina Notman takes a look at the recent and upcoming diagnostic and screening innovations aiming to drive down the incidence of tuberculosis globally
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ResearchExplainer: What are water microdroplets and why are chemists talking about them?
Researchers are struggling to agree on the underlying reasons for accelerated rates and altered reaction mechanisms in water microdroplets. Here’s what we do know and where open questions lie…
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BusinessIllumina to give up Grail as competition appeals fail
Sequencing giant will sell off its former spin-out in accordance with regulator orders
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BusinessPharmaceuticals roundup 2023
Regulatory and pricing reforms have topped industry agendas in 2023, while weight loss drugs surged and Covid-19 therapies waned
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ResearchInvasive zebra mussels’ unique sticky threads unraveled
New understanding of byssal threads finds similarities with spider silk making them unlike any other mussels’
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BusinessDanaher completes $5.7 billion Abcam acquisition
Deal proceeded despite significant opposition from founder and ex-chief Jonathan Milner
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ResearchHigh mercury levels in tropical birds in Americas blamed on gold mining
Exotic birds are the canary in the gold mine when it comes to mercury pollution and provide warning that other animals, including humans, affected
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ResearchBiocatalysis breakthrough enables synthesis of lactam building blocks for drugs
Enzymatic cyclisation of oxazolone reagents offers a cheap and simple route to important antibiotic precursor
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ResearchMolecular movie captures DNA repair from start to finish
Study spans pico- to microsecond timescales to uncover enzymatic process
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ResearchDNA-damaging device could make mutant discovery safer and simpler
Cool microplasma jets create a stream of radicals that induce mutations
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BusinessUK becomes first country in the world to authorise a Crispr-based gene therapy
Treatment aims to cure patients with β-thalassaemia and sickle-cell disease
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NewsFisheries agency concludes it’s ‘very unlikely’ pyridine behind UK crustacean deaths after new tests
Cause of mass die-offs in late 2021 and early 2022 still a mystery
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ResearchSynthetic yeast genome project creates strain with over 50% synthetic DNA
Entirely artificial organism opens up door to designer yeast with biotechnology applications